Associations between fentanyl use and initiation, persistence, and retention on medications for opioid use disorder among people living with uncontrolled HIV disease.

ABSTRACT:

Background

Associations between fentanyl use and initiation and retention on medications for opioid use disorder (MOUD) are poorly understood.

Methods

Data were from a multisite clinical trial comparing extended-release naltrexone (XR-NTX) with treatment as usual (TAU; buprenorphine or methadone) to achieve HIV viral suppression among people with OUD and uncontrolled HIV disease. The exposure of interest was fentanyl use, as measured by urine drug screening. Outcomes were time to MOUD initiation, defined as date of first injection of XR-NTX, buprenorphine prescription, or methadone administration; MOUD persistence, the total number of injections, prescriptions, or administrations received over 24 weeks; and MOUD retention, having an injection, prescription, or administration

SUBMITTER: Cook RR 

PROVIDER: S-EPMC8595584 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature