Dietary fluoride intake during pregnancy and neurodevelopment in toddlers: A prospective study in the progress cohort.

ABSTRACT: Foods and beverages provide a source of fluoride exposure in Mexico. While high fluoride concentrations are neurotoxic, recent research suggests that exposures within the optimal range may also pose a risk to the developing brain. This prospective study examined whether dietary fluoride intake during pregnancy is associated with toddlers' neurodevelopment in 103 mother-child pairs from the PROGRESS cohort in Mexico City. Food and beverage fluoride intake was assessed in trimesters 2 and 3 using a food frequency questionnaire and Mexican tables of fluoride content. We used the Bayley-III to evaluate cognitive, motor, and language outcomes at 12 and 24 months of age. Adjusted linear regression models were generated for each neurodevelopment assessment time point (12 and 24 months). Mixed-eff

SUBMITTER: Cantoral A 

PROVIDER: S-EPMC8595627 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature