Effects of financial incentives on volunteering for clinical trials: A randomized vignette experiment.

ABSTRACT:

Background

Financial incentives may aid recruitment to clinical trials, but evidence regarding risk/burden-driven variability in participant preferences for incentives is limited. We developed and tested a framework to support real-world decisions on recruitment budget.

Methods

We included two phases: an Anchoring Survey, to ensure we could capture perceived unpleasantness on a range of life events, and a Vignette Experiment, to explore relationships between financial incentives and participants' perceived risk/burden and willingness to participate in high- and low-risk/burden versions of five vignettes drawn from common research activities. We compared vignette ratings to identify similarly rated life events from the Anchoring Survey to contextualize ratings of study risk.<

SUBMITTER: Bickman L 

PROVIDER: S-EPMC8595781 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature