Partially linear single-index generalized mean residual life models.

ABSTRACT: Mean residual life (MRL) function defines the remaining life expectancy of a subject who has survived to a time point and is an important alternative to the hazard function for characterizing the distribution of a time-to-event variable. Existing MRL models primarily focus on studying the association between risk factors and disease risks using linear model specifications in multiplicative or additive scale. When risk factors have complex correlation structures, nonlinear effects, or interactions, the prefixed linearity assumption may be insufficient to capture the relationship. Single-index modeling framework offers flexibility in reducing dimensionality and modeling nonlinear effects. In this article, we propose a class of partially linear single-index generalized MRL models, the regress

SUBMITTER: Jin P 

PROVIDER: S-EPMC8595843 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature