A supercritical fluid workflow for the quality assessment of herbal drugs and commercial preparations from Rhodiola rosea.

ABSTRACT:

Introduction

Preparations from the Rhodiola rosea are experiencing an increase in popularity: extracts of dried roots and rhizomes are used as adaptogen to treat stress, fatigue, and weakness. To meet high pharmaceutical standards, fast and reliable methods to assess phytochemical variations in respect of quality control are needed.

Objective

The aim of this study was to extract and quantify seven characteristic secondary metabolites of R. rosea, namely p-tyrosol (1), rosin (2), rosiridin (3), salidroside (4), rosarin (5), rosavin (6), and tricin-5-O-β-d-glucopyranoside (7) in 24 herbal drugs and seven commercial preparations using a newly established supercritical fluid workflow.

Methods

The developed protocol allowed for an exhaustive extraction of compounds 1-7 usi

SUBMITTER: Langeder J 

PROVIDER: S-EPMC8596633 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature