Impact of ultraviolet radiation and exposome on rosacea: Key role of photoprotection in optimizing treatment.

ABSTRACT:

Background

Pathophysiology of rosacea is not completely understood and involves a complex interaction among genetics, ultraviolet (UV) light, microorganisms, impaired skin barrier, neuronal and vascular dysfunction, and immune system disruption.

Aims

To describe the etiology of rosacea with an emphasis on the role of UV radiation and exposome, and to review the importance of non-pharmacologic strategies focusing on photoprotection.

Methods

We conducted a narrative review of the literature. We performed literature searches with PubMed from January 1990 to November 2020 using the keywords "rosacea", "pathogenesis", "ultraviolet radiation", "exposome", "photoprotection", "sunscreens" and "non-pharmacologic agents". The search was limited to English, Spanish, and French l

SUBMITTER: Morgado-Carrasco D 

PROVIDER: S-EPMC8596706 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature