Relationship Between Magnetic Resonance Imaging Features and Knee Pain Over Six Years in Knees Without Radiographic Osteoarthritis at Baseline.

ABSTRACT:

Objective

To explore whether magnetic resonance imaging (MRI) features suggestive of knee osteoarthritis (OA) are associated with presence of knee pain in possible early-stage OA development.

Methods

We included 294 participants from the Osteoarthritis Initiative (mean ± SD age 50 ± 3 years; 50% women) with baseline Kellgren/Lawrence grade of 0 in both knees, all of whom had received knee MRIs at 4 different time points over 6 years (baseline, 24, 48, and 72 months). Using a linear mixed model (knees matched within individuals), we studied whether MRI features (meniscal body extrusion [in mm], cartilage area loss [score 0-39], cartilage full thickness loss [range 0-16], osteophytes [range 0-29], meniscal integrity [range 0-10], bone marrow lesions [BMLs] including bone marro

SUBMITTER: Magnusson K 

PROVIDER: S-EPMC8596875 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature