Adiponectin gene polymorphisms and risk of type 2 diabetes: an updated evidence for meta-analysis.

ABSTRACT:

Background

Growing body of evidence suggest the association between SNP - 11377 C > G and SNP + 276 G > T polymorphisms of adiponectin gene with type 2 diabetes (T2D). However, these findings have not been conclusive and consistent. The present study quantitatively evaluates the data on the association between DIPOQ - 11377C/G, and + 276G/T polymorphisms and risk of T2D through a meta-analysis.

Methods

A systematic search was performed in the PubMed, Web of science, Scopus and Cochrane library databases to extract published studies according to the inclusion criteria. Among the 741 studies, 391 of them were screened as full text and 31 studies were finally included in the meta-analysis. Analysis of data was performed using random-effects model. Odds ratios (ORs) with 95% con

SUBMITTER: Alimi M 

PROVIDER: S-EPMC8596906 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature