The timing of administering aspirin and nitroglycerin in patients with STEMI ECG changes alter patient outcome.

ABSTRACT:

Background

Both chewed aspirin and sublingual nitroglycerin are fast acting medications and reach therapeutic levels within a few minutes. Current guidelines for managing acute coronary syndrome (ACS) do not recognize the importance of the order or timing of administering aspirin and nitroglycerin. This retrospective study aimed to examine if there was any benefit to the timing of giving aspirin before or after nitroglycerin in cases of ACS.

Methods

From the large National Emergency Medical Services Information System (NEMSIS) 2017 Version database, 2594 patients with acute coronary syndrome were identified (based on chest pain and their ECG finding) that received aspirin plus nitroglycerin in prehospital settings. Based on which medication was given first, the patients were

SUBMITTER: Todoroski KB 

PROVIDER: S-EPMC8597308 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature