Research algorithm for the detection of genetic patterns and phenotypic variety of non-syndromic dental agenesis.

ABSTRACT:

Introduction

Dental agenesis (DA), brings together the anodontia, oligodontia, hypodontia, characterized by a deficit in the development of a variable number of teeth. The objectives of the study were to illustrate the phenotypic variability of non-syndromic DA, to identify cases of DA with hereditary genetic transmission, and establish the mode of DA genetic pattern in these cases, together with the determination of DA prevalence in the population group study.

Patients, materials and methods

The cross-sectional observational study was performed on a mixed population group, consisting of 861 Caucasian patients, between January 2018-December 2019. The clinical evaluation protocol of patients with DA, used to illustrate their phenotype, included the following stages: oral exam

SUBMITTER: Albu CC 

PROVIDER: S-EPMC8597362 | biostudies-literature | 2021 Jan-Mar

REPOSITORIES: biostudies-literature