Genetics of Smoking Behaviors in American Indians.

ABSTRACT:

Background

The smoking behavior of American Indians (AI) differs from that of non-Hispanic whites (NHW). Typically light smokers, cessation interventions in AIs are generally less effective. To develop more effective cessation programs for AIs, clinicians, researchers, and public health workers need a better understanding of the genetic factors involved in their smoking behavior. Our aim was to assess whether SNPs associated with smoking behavior in NHWs are also associated with smoking in AIs.

Methods

We collected questionnaire data on smoking behaviors and analyzed blood and saliva samples from two Tribal populations with dramatically different cultures and smoking prevalence, one in the Northern Plains (n = 323) and the other in the Southwest (n = 176). A to

SUBMITTER: Henderson JA 

PROVIDER: S-EPMC8597394 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature