Lack of Association Between Recent Cannabis Use and Advanced Liver Fibrosis Among HIV-positive Heavy Drinkers.

ABSTRACT:

Aim

This study aimed to analyze the association between any past-month cannabis use and advanced liver fibrosis.

Background

Cannabinoid receptors play a role in acute and chronic liver injury, but human studies addressing the impact of cannabis use on liver fibrosis have shown mixed results.

Objective

The objective of this study was to explore and estimate the association between pastmonth cannabis use and advanced liver fibrosis (ALF) in a cohort of Russian HIV-positive individuals with heavy alcohol use and a high prevalence of hepatitis C virus (HCV) coinfection.

Methods

Baseline data were analyzed from participants of the ZINC study, a trial that enrolled HIV-positive Russian patients without prior antiretroviral therapy. Cannabis use during the prior month

SUBMITTER: Fuster D 

PROVIDER: S-EPMC8597417 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature