Fetal cerebral blood-flow redistribution: analysis of Doppler reference charts and association of different thresholds with adverse perinatal outcome.

ABSTRACT:

Objectives

First, to compare published Doppler reference charts of the ratios of flow in the fetal middle cerebral and umbilical arteries (i.e. the cerebroplacental ratio (CPR) and umbilicocerebral ratio (UCR)). Second, to assess the association of thresholds of CPR and UCR based on these charts with short-term composite adverse perinatal outcome in a cohort of pregnancies considered to be at risk of late preterm fetal growth restriction.

Methods

Studies presenting reference charts for CPR or UCR were searched for in PubMed. Formulae for plotting the median and the 10^th percentile (for CPR) or the 90^th percentile (for UCR) against gestational age were extracted from the publication or calculated from the published tables. Data from a prospective Europea

SUBMITTER: Wolf H 

PROVIDER: S-EPMC8597586 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature