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NCutYX: a package for clustering analysis of multilayer omics data.


ABSTRACT: Multilayer omics profiling has become a major venue for understanding complex diseases. We develop NCutYX, an R package for clustering analysis of multilayer omics data. The package and methods jointly analyze multiple layers of omics measurements and effectively accommodate their regulations. They systematically conduct a series of analysis based on the normalized cut technique, including the clusterings of subjects and omics measurements and biclustering. The package can be valuable for its timely context, novel methods, and comprehensiveness. https://cran.r-project.org/web/packages/NCutYX/. Supplementary data are available at Bioinformatics online.

SUBMITTER: Teran Hidalgo SJ 

PROVIDER: S-EPMC8597621 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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NCutYX: a package for clustering analysis of multilayer omics data.

Teran Hidalgo Sebastian J SJ   Wu Mengyun M   Ma Shuangge S  

Bioinformatics (Oxford, England) 20191115


<h4>Summary</h4>Multilayer omics profiling has become a major venue for understanding complex diseases. We develop NCutYX, an R package for clustering analysis of multilayer omics data. The package and methods jointly analyze multiple layers of omics measurements and effectively accommodate their regulations. They systematically conduct a series of analysis based on the normalized cut technique, including the clusterings of subjects and omics measurements and biclustering. The package can be val  ...[more]

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