Influence of Factors Altering Gastric Microbiota on Bariatric Surgery Metabolic Outcomes.

ABSTRACT: Little is known about the influence of gastric microbiota on host metabolism, even though the stomach plays an important role in the production of hormones involved in body weight regulation and glucose homeostasis. Proton pump inhibitors (PPIs) and Helicobacter pylori alter gut microbiota, but their impact on gastric microbiota in patients with obesity and the influence of these factors on the metabolic response to bariatric surgery is not fully understood. Forty-one subjects with morbid obesity who underwent sleeve gastrectomy were included in this study. The H. pylori group was established by the detection of H. pylori using a sequencing-based method (n = 16). Individuals in whom H. pylori was not detected were classified according to PPI treatment. Gastric biopsy specimens were

SUBMITTER: Gutierrez-Repiso C 

PROVIDER: S-EPMC8597636 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature