Risk factors for functional decline among survivors of Gram-negative bloodstream infection: A prospective cohort study.

ABSTRACT:

Objective

To identify risk factors for functional decline after hospitalization for Gram-negative bacteremia.

Patients and methods

A prospective cohort study based on a randomized controlled trial conducted between January 1, 2013 and August 31, 2017 in Israel and Italy. Hospitalized patients with Gram-negative bacteremia who survived until day 90 and were not bedridden at baseline were included. The primary end point was functional decline at 90 days.

Results

Five hundred and nine patients were included. The median age of the cohort was 71 years (interquartile range [IQR], 60-80 years), 46.4% (236/509) were male and 352 of 509 (69%) patients were independent at baseline. Functional decline at 90 days occurred in 24.4% of patients (124/509). In multivariable analysis;

SUBMITTER: Turjeman A 

PROVIDER: S-EPMC8598031 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature