Berberis Vulgaris Fruit: Determination of Phenolic Compounds in Extracts Obtained by Supercritical CO₂ and Soxhlet Methods Using HPLC.

ABSTRACT: Recently, research studies on nutraceutically important polyphenolic substances have attracted intensive attention. Berberis vulgaris is an important source of polyphenolic compounds and is often used in traditional medicine. In this study, the extraction of rutin and apigenin rich oil from Berberis vulgaris fruits was evaluated by supercritical carbon dioxide (Sc-CO₂) extraction method with and without co-solvent. As valuable antioxidants, rutin and apigenin content of extracts were analyzed by HPLC, and their amounts were maximized via parametric optimization. The rutin compound studied in this research has the potential to be a drug against the COVID-19 virus. The operating conditions were considered in the range of 35-70 °C temperatures, 140-240 bar of pressure

SUBMITTER: Nuralın L 

PROVIDER: S-EPMC8598104 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature