Synthesis of a comprehensive population code for contextual features in the awake sensory cortex.

ABSTRACT: How cortical circuits build representations of complex objects is poorly understood. Individual neurons must integrate broadly over space, yet simultaneously obtain sharp tuning to specific global stimulus features. Groups of neurons identifying different global features must then assemble into a population that forms a comprehensive code for these global stimulus properties. Although the logic for how single neurons summate over their spatial inputs has been well explored in anesthetized animals, how large groups of neurons compose a flexible population code of higher-order features in awake animals is not known. To address this question, we probed the integration and population coding of higher-order stimuli in the somatosensory and visual cortices of awake mice using two-photon calcium

SUBMITTER: Lyall EH 

PROVIDER: S-EPMC8598168 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature