Convalescent plasma therapy in obese severe COVID-19 adolescents: Two cases report.

ABSTRACT:

Background

In Indonesia, 175 cases resulted in death in children from March to December 2020. Studies regarding Convalescent Plasma Therapy's (CPT) safety and efficacy in children are scarce. Our case report was the first to write CPT in Indonesian children.

Case presentation

In our case, two obese children with progressive shortness of breath, worsening cough, and high fever, the findings met severe COVID-19 criteria. We performed CPT for these patients and the patient's condition was improved and able to be discharged.

Discussion

Severe COVID-19 with or without comorbid was the indication of CPT which had been approved by the U.S. FDA and Indonesian Pediatrics Society. The key factors associated with CPT efficacy were the donor's titer antibody, the treatment time p

SUBMITTER: Cesilia C 

PROVIDER: S-EPMC8598255 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature