Antioxidants Associated With Oncogenic Human Papillomavirus Infection in Women.

ABSTRACT:

Background

Human papillomavirus (HPV) infection is a major cause of cervical cancer. Studies showed the onset of HPV carcinogenesis may be induced by oxidative stress affecting the host immune system. The association between antioxidants and oncogenic HPV remains unclear. In this study, we aim to identify antioxidants associated with vaginal HPV infection in women.

Methods

The associations between the 15 antioxidants and vaginal HPV infection status (no, low-risk [LR], and high-risk [HR] HPV) were evaluated using 11 070 women who participated in the 2003-2016 National Health and Nutrition Examination Survey (NHANES).

Results

We identified serum albumin and 4 dietary antioxidants (vitamin A, B2, E, and folate) inversely associated with HR-HPV infection. Women with a lo

SUBMITTER: Lin HY 

PROVIDER: S-EPMC8599710 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature