Major Adverse Cardiovascular Events During Invasive Pneumococcal Disease Are Serotype Dependent.

ABSTRACT:

Background

Up to 30% of patients admitted to hospitals with invasive pneumococcal disease (IPD) experience major adverse cardiovascular event (MACE) including new/worsening heart failure, new/worsening arrhythmia, and/or myocardial infarction. Streptococcus pneumoniae (Spn) is the most frequently isolated bacterial pathogen among community-acquired pneumonia (CAP) patients and the only etiological agent linked independently to MACE. Nevertheless, no clinical data exist identifying which serotypes of Spn are principally responsible for MACE.

Methods

This was an observational multicenter retrospective study conducted through the Public Health Secretary of Bogotá, Colombia. We included patients with a confirmed clinical diagnosis of IPD with record of pneumococcal serotyping an

SUBMITTER: Africano HF 

PROVIDER: S-EPMC8599727 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature