Clinical course of 602 patients with Takayasu's arteritis: comparison between Childhood-onset versus adult onset disease.

ABSTRACT:

Objectives

To describe the clinical profile of Asian Indian patients with Takayasu's arteritis (TAK) and to compare clinical features and outcome of childhood-onset Takayasu's arteritis (cTAK) with adult-onset TAK (aTAK).

Methods

Data related to clinical features and response to treatment of patients with cTAK (age of onset <16 years) and aTAK from a large observational cohort in our tertiary care teaching hospital were noted and compared.

Results

Altogether, 602 patients (cTAK = 119; aTAK = 483) were studied. Patients with cTAK had a blunted female: male ratio; but fever, elevated acute phase reactants, involvement of abdominal aorta or its branches, hypertension, abdominal pain, elevated serum creatinine and cardiomyopathy were more common in cTAK as compared with a

SUBMITTER: Danda D 

PROVIDER: S-EPMC8599811 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature