Clinical outcomes and temporal trends of immunological and non-immunological rare diseases in adult kidney transplant.

ABSTRACT:

Background

Rare diseases (RDs) encompass many difficult-to-treat conditions with different characteristics often associated with end-stage renal disease (ESRD). However, data about transplant outcomes in adult patients are still lacking and limited to case reports/case series without differentiation between immunological/non-immunological RDs.

Methods

Retrospective analysis among all adult kidney transplanted patients (KTs) with RDs (RDsKT group) performed in our high-volume transplantation center between 2005 and 2016. RDs were classified according to the Orphanet code system differentiating between immunological and non-immunological diseases, also comparing clinical outcomes and temporal trends to a control population without RDs (nRDsKT).

Results

Among 1381 KTs, 3

SUBMITTER: Gallo E 

PROVIDER: S-EPMC8600810 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature