Genetic optimisation of bacteria-induced calcite precipitation in Bacillus subtilis.

ABSTRACT:

Background

Microbially induced calcite precipitation (MICP) is an ancient property of bacteria, which has recently gained considerable attention for biotechnological applications. It occurs as a by-product of bacterial metabolism and involves a combination of chemical changes in the extracellular environment, e.g. pH increase, and presence of nucleation sites on the cell surface or extracellular substances produced by the bacteria. However, the molecular mechanisms underpinning MICP and the interplay between the contributing factors remain poorly understood, thus placing barriers to the full biotechnological and synthetic biology exploitation of bacterial biomineralisation.

Results

In this study, we adopted a bottom-up approach of systematically engineering Bacillus subtilis

SUBMITTER: Hoffmann TD 

PROVIDER: S-EPMC8600894 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature