Factors Associated with Resection and Survival After Laparoscopic HIPEC for Peritoneal Gastric Cancer Metastasis.

ABSTRACT:

Purpose

Although laparoscopic hyperthermic intraperitoneal chemotherapy (LS-HIPEC) has been proven safe in patients with gastric adenocarcinoma and carcinomatosis or positive cytology, patient selection criteria remain unclear. Thus, we perform a retrospective analysis to identify factors associated with improved survival and resection rates.

Patients and methods

Data for all patients undergoing LS-HIPEC for stage IV gastric adenocarcinoma between June 2014 and November 2018 were collected prospectively and analyzed for associations with survival and resection using uni- and multivariate logistic regression, Cox proportional hazards models, and Kaplan-Meier survival functions.

Results

Of 70 patients who underwent LS-HIPEC, 43 (61%) received two drugs (mitomycin C and

SUBMITTER: White MG 

PROVIDER: S-EPMC8601118 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature