Regional Cortical Thickness Predicts Top Cognitive Performance in the Elderly.

ABSTRACT: While aging is typically associated with cognitive decline, some individuals are able to diverge from the characteristic downward slope and maintain very high levels of cognitive performance. Prior studies have found that cortical thickness in the cingulate cortex, a region involved in information processing, memory, and attention, distinguish those with exceptional cognitive abilities when compared to their cognitively more typical elderly peers. Others major areas outside of the cingulate, such as the prefrontal cortex and insula, are also key in successful aging well into late age, suggesting that structural properties across a wide range of areas may better explain differences in cognitive abilities. Here, we aim to assess the role of regional cortical thickness, both in the cingulate

SUBMITTER: Dominguez EN 

PROVIDER: S-EPMC8601448 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature