Profiling of inflammatory cytokines in patients with caustic gastrointestinal tract injury.

ABSTRACT:

Introduction

Study of inflammatory cytokines in patients with caustic gastrointestinal tract injury is sketchy. This study investigated the cytokine profiling of patients with caustic substance ingestion, and analyzed the differences between patients with severe and mild injury.

Methods

This prospective, cross-sectional study enrolled 22 patients admitted to Chang Gung Memorial Hospital between March and October 2018. All patients underwent esophagogastroduodenoscopy in 24 hours. Patients were categorized into two subgroups, as mild (<2b, n = 11) or severe (≥2b, n = 11) group.

Results

The neutrophil count was higher in severe than mild group (P = 0.032). Patients in mild and severe groups exhibited significantly higher circulating inflammatory cytokines than healthy c

SUBMITTER: Cheng HT 

PROVIDER: S-EPMC8601450 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature