Comparison of risk profiles for new-onset atrial fibrillation between patients aged <60 and ≥60 years.

ABSTRACT:

Background

Atrial fibrillation (AF) has a heterogeneous pathophysiology according to individual patient characteristics. This study aimed to identify the effects of widely known risk factors on AF incidence according to age and to elucidate the clinical implications of these effects.

Methods and results

We analyzed data from 501,668 subjects (≥18years old) without AF and valvular heart disease from the Korean National Health Insurance Service-National Sample Cohort. The total population was divided into two groups according to age, <60years and ≥60years. AF occurred in 0.7% of the overall population (3,416 of 501,668) during the follow-up period (mean 47.6 months). In Cox regression analysis, age, male sex, previous ischemic stroke, heart failure, and hypertension were relat

SUBMITTER: Kim IS 

PROVIDER: S-EPMC8601466 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature