Photoelectrocatalytic C-H halogenation over an oxygen vacancy-rich TiO₂ photoanode.

ABSTRACT: Photoelectrochemical cells are emerging as powerful tools for organic synthesis. However, they have rarely been explored for C-H halogenation to produce organic halides of industrial and medicinal importance. Here we report a photoelectrocatalytic strategy for C-H halogenation using an oxygen-vacancy-rich TiO₂ photoanode with NaX (X=Cl^-, Br^-, I^-). Under illumination, the photogenerated holes in TiO₂ oxidize the halide ions to corresponding radicals or X₂, which then react with the substrates to yield organic halides. The PEC C-H halogenation strategy exhibits broad substrate scope, including arenes, heteroarenes, nonpolar cycloalkanes, and aliphatic hydrocarbons. Experimental and theoretical data reveal that the oxygen vacan

SUBMITTER: Li Z 

PROVIDER: S-EPMC8602285 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature