Epidemiology, Outcomes, and Trends of Patients With Sepsis and Opioid-Related Hospitalizations in U.S. Hospitals.

ABSTRACT:

Objectives

Widespread use and misuse of prescription and illicit opioids have exposed millions to health risks including serious infectious complications. Little is known, however, about the association between opioid use and sepsis.

Design

Retrospective cohort study.

Setting

About 373 U.S. hospitals.

Patients

Adults hospitalized between January 2009 and September 2015.

Interventions

None.

Measurements and main results

Sepsis was identified by clinical indicators of concurrent infection and organ dysfunction. Opioid-related hospitalizations were identified by the International Classification of Diseases, 9th Revision, Clinical Modification codes and/or inpatient orders for buprenorphine. Clinical characteristics and outcomes were compared by sepsi

SUBMITTER: Alrawashdeh M 

PROVIDER: S-EPMC8602712 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature