Fecal microbiota profiling in irritable bowel syndrome and inflammatory bowel disease patients with irritable bowel syndrome-type symptoms.

ABSTRACT:

Background

The intestinal microbiota is thought to be involved in the occurrence of inflammatory bowel disease in remission with irritable bowel syndrome (IBS)-type symptoms, but the specific distinct profile of these bacteria remains unclear. This cross-sectional study aims to investigate the fecal microbiota profiling in patients with these diseases.

Methods

Fecal samples from 97 subjects, including Crohn's disease patients in remission with IBS-type symptoms (CDR-IBS⁺) or without IBS-type symptoms (CDR-IBS^-), ulcerative colitis patients in remission with IBS-type symptoms (UCR-IBS⁺) or without IBS-type symptoms (UCR-IBS^-), IBS patients and healthy controls, were collected and applied 16S ribosomal DNA (rDNA) gene sequencing. The

SUBMITTER: Cui X 

PROVIDER: S-EPMC8603515 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature