Autologous Platelet Concentrate of 2^nd and 3^rd generations efficacy in the surgical treatment of gingival recession: an overview of systematic reviews.

ABSTRACT:

Background

Autologous platelet concentrate (APC)/platelet-rich fibrin (PRF) of second and third generations has increased use in periodontics to optimize wound healing. Few systematic reviews (SRs) have reported improved clinical outcomes, while other studies reported significantly better results for the connective tissue graft (CTG). There is still unclear clinical evidence about APC/PRF use to treat gingival recession (GR) defects. Then, the purpose of this SR was to evaluate the use of APC/PRF membranes (2^nd and 3^rd generations) in root coverage (RC) procedures and assess its efficacy as a substitute biomaterial.

Materials and methods

An electronic search was conducted in PubMed, Cochrane Central, Web of Science, Google Scholar, BookSC databases, and

SUBMITTER: Fernandes GVO 

PROVIDER: S-EPMC8603797 | biostudies-literature | 2021 Nov-Dec

REPOSITORIES: biostudies-literature