The impact of active case finding on transmission dynamics of tuberculosis: A modelling study.

ABSTRACT:

Background

In the last decade, active case finding (ACF) strategies for tuberculosis (TB) have been implemented in many diverse settings, with some showing large increases in case detection and reporting at the sub-national level. There have also been several studies which seek to provide evidence for the benefits of ACF to individuals and communities in the broader context. However, there remains no quantification of the impact of ACF with regards to reducing the burden of transmission. We sought to address this knowledge gap and quantify the potential impact of active case finding on reducing transmission of TB at the national scale and further, to determine the intensification of intervention efforts required to bring the reproduction number (R0) below 1 for TB.

Methods

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SUBMITTER: Ayabina DV 

PROVIDER: S-EPMC8604297 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature