Impact of Escherichia coli probiotic strains ED1a and Nissle 1917 on the excretion and gut carriage of extended-spectrum beta-lactamase-producing E. coli in pigs.

ABSTRACT: We evaluated the impact of the administration of two Escherichia coli probiotic strains (ED1a and Nissle 1917) to pigs on the gut carriage or shedding of extended-spectrum beta-lactamase-producing E. coli. The probiotics were given to four sows from 12 days before farrowing to the weaning day, and to the 23 piglets (infected treated group (IPro)) from birth to the age of 49 days. Four other sows and their 24 piglets (infected non-treated group (INT)) did not receive the probiotics. IPro and INT piglets (n = 47) were orally inoculated with the strain E. coli 17-348F-RifR carrying the bla _CTX-M-1 gene and resistant to rifampicin. Cefotaxime-resistant (CTX^R) E. coli and rifampicin-resistant (Rif^R) E. coli were c

SUBMITTER: Mourand G 

PROVIDER: S-EPMC8604716 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature