Age dependent neural correlates of inhibition and control mechanisms in moderate to heavy drinkers.

ABSTRACT:

Background

Long-term, heavy alcohol consumption has been associated with impairments in control over alcohol use, but whether this extends to other areas of cognitive and behavioral control such as response inhibition remains unclear. Understanding individual differences in the neural correlates of response inhibition will provide further insight into the neurobiology of heavy drinking. The current study investigated response inhibition in a large sample of moderate to heavy drinkers METHODS: One hundred fifty-three individuals completed a stop signal task while undergoing functional magnetic resonance imaging. Multiple regression analyses focused on blood oxygen level-dependent (BOLD) response contrasts of correct inhibition and failed inhibition as dependent variables and include

SUBMITTER: Swartz M 

PROVIDER: S-EPMC8604718 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature