Associations of periodontal disease and tooth loss with all-cause and cause-specific mortality in the Sister Study.

ABSTRACT:

Aim

Studies have found that periodontal disease and tooth loss are associated with increased mortality; however, associations with cause-specific mortality and all-cause mortality within specific subgroups have not been thoroughly investigated.

Materials and methods

We examined the association of self-reported periodontal disease and disease/decay-related tooth loss with subsequent all-cause and cause-specific mortality in the Sister Study, a prospective cohort study of 50,884 women aged 35-74 years at baseline, whose sister was diagnosed with breast cancer. Hazard ratios (HRs) and 95% confidence intervals (95% CIs) for the associations were calculated with adjustment for relevant confounders.

Results

With a mean follow-up of 10.9 years (range 0.1-14.3), 2058 women di

SUBMITTER: Wu Z 

PROVIDER: S-EPMC8604772 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature