Resting-state network topology characterizing callous-unemotional traits in adolescence.

ABSTRACT:

Background

Callous-unemotional (CU) traits, a youth antisocial phenotype, are hypothesized to associate with aberrant connectivity (dis-integration) across the salience (SAL), default mode (DMN), and frontoparietal (FPN) networks. However, CU traits have a heterogeneous presentation and previous research has not modeled individual heterogeneity in resting-state connectivity amongst adolescents with CU traits. The present study models individual-specific network maps and examines topological features of individual and subgroup maps in relation to CU traits.

Methods

Participants aged 13-17 (n = 84, male = 55%, female = 45%) completed resting-state functional connectivity and the inventory of callous-unemotional traits as part of the Nathan Klein Rockland study. A sparse networ

SUBMITTER: Winters DE 

PROVIDER: S-EPMC8604808 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature