Central nervous system vasculopathy and Seckel syndrome: case illustration and systematic review.

ABSTRACT:

Purpose

To systematically review reported cases of Seckel syndrome (SS) and point out cases associated with central nervous system (CNS) vasculopathy and provide a summary of their clinical presentation, management, and outcomes including our illustrative case.

Methods

We conducted a search on the MEDLINE, PubMed, Google Scholar, and Cochrane databases using the keywords "Seckel + syndrome." We identified 127 related articles reporting 252 cases of SS apart from our case. Moreover, we searched for SS cases with CNS vasculopathies from the same databases. We identified 7 related articles reporting 7 cases of CNS vasculopathies in SS patients.

Results

The overall rate of CNS vasculopathy in SS patients is 3.16% (n = 8/253), where moyamoya disease (MMD) accounted for 1.9

SUBMITTER: Khojah O 

PROVIDER: S-EPMC8604825 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature