Ontology highlight
ABSTRACT:
SUBMITTER: Sharma NK
PROVIDER: S-EPMC8605353 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Sharma Nitesh Kumar NK Gupta Sagar S Kumar Ashwani A Kumar Prakash P Pradhan Upendra Kumar UK Shankar Ravi R
iScience 20211030 12
Identifying the factors determining the RBP-RNA interactions remains a big challenge. It involves sparse binding motifs and a suitable sequence context for binding. The present work describes an approach to detect RBP binding sites in RNAs using an ultra-fast inexact k-mers search for statistically significant seeds. The seeds work as an anchor to evaluate the context and binding potential using flanking region information while leveraging from Deep Feed-forward Neural Network. The developed mod ...[more]