Early Onset and Maintenance Effect of Galcanezumab in Japanese Patients with Episodic Migraine.

ABSTRACT:

Purpose

This study aimed to extensively evaluate the onset and maintenance effect of galcanezumab compared with placebo for the prevention of episodic migraine in Japanese patients.

Patients and methods

This was a post-hoc analysis of a Phase 2, multicenter, randomized, double-blind, placebo-controlled study conducted between December 2016 and January 2019 (ClinicalTrials.gov: NCT02959177). Patients aged between 18 and 65 years with episodic migraine were randomized to receive a monthly injection of galcanezumab (120 mg: N = 115, 240 mg: N = 114) or placebo (N = 230) for 6 months. Outcome measures included onset of effect at weekly and daily intervals-assessed by change from baseline in the number of migraine headache days and the proportion of patients with migraine headach

SUBMITTER: Igarashi H 

PROVIDER: S-EPMC8605884 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature