Evolutionary Perspective and Theories on the Possible Origin of SARS-CoV-2.

ABSTRACT:

Objective

From the currently available next-generation sequencing data, we have tried to analyze different theories on the origin of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and thereby to identify the origin of its intermediate host. Genome sequence-based phylogenetic analysis and multiple sequence alignment were performed.

Methods

We used the Virus Pathogen Resource (ViPR) platform for phylogenetic analysis and the MUltiple Sequence Comparison by Log- Expectation (MUSCLE) algorithm for whole genome sequence alignment of SARS-CoV-2, severe acute respiratory syndrome coronavirus (SARS-CoV), BJ01, Middle East respiratory syndrome coronavirus (MERS-CoV), bat coronavirus RaTG13, and pangolin coronavirus.

Results

From these two analyses, we have found

SUBMITTER: Saeed AA 

PROVIDER: S-EPMC8606195 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature