Cross-sectional genomic perspective of epidemic waves of SARS-CoV-2: A pan India study.

ABSTRACT:

Background

COVID-19 has posed unforeseen circumstances and throttled major economies worldwide. India has witnessed two waves affecting around 31 million people representing 16% of the cases globally. To date, the epidemic waves have not been comprehensively investigated to understand pandemic progress in India.

Objective

Here, we aim for pan Indian cross-sectional evolutionary analysis since inception of SARS-CoV-2.

Methods

High quality genomes, along with their collection date till 26th July 2021, were downloaded. Whole genome-based phylogeny was obtained. Further, the mutational analysis was performed using SARS-CoV-2 first reported from Wuhan (NC_045512.2) as reference.

Results

Based on reported cases and mutation rates, we could divide the Indian epidemic

SUBMITTER: Kumar S 

PROVIDER: S-EPMC8606321 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature