The Clinicopathological Features and Overall Survival of Patients With Gastric Neuroendocrine Carcinoma.

ABSTRACT:

Objectives

Gastric neuroendocrine carcinoma (GNEC) is a class of rare histological subtypes in gastric cancer (GC). This retrospective case-control study aimed to explore the clinicopathological features and overall survival (OS) of patients with GNEC.

Methods

A large population of GNEC and intestinal-type GC (IGC) patients were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. The 1:1 propensity score matching (PSM) analysis was initiated to adjust the confounders between GNEC and IGC cohorts. Kaplan-Meier (KM) plots with log-rank tests were used to compare the survival differences in GNEC versus IGC. Additionally, Cox proportional hazard regression models were adopted to characterize the prognostic factors relevant to OS of the GNEC patients.<

SUBMITTER: Xu B 

PROVIDER: S-EPMC8606720 | biostudies-literature | 2021 Jan-Dec

REPOSITORIES: biostudies-literature