Association between serum PGE₂ levels and degree of acid-fast bacilli positivity in sputum of pulmonary tuberculosis patients.

ABSTRACT:

Background

Mycobacterium tuberculosis that infected apoptotic macrophages is triggered by PGE₂. Apoptosis suppresses the growth of Mycobacterium tuberculosis bacteria, which is shown in the results of acid-fast bacilli (AFB) in the sputum that becomes a marker of the number of bacteria.

Objective

Analyzing the association between serum PGE₂ levels and the positivity of AFB in the sputum of tuberculosis patients.

Methods

A cross-sectional study was carried out from August 2019-July 2020. Serum PGE₂ levels and AFB levels in sputum were collected from participants. Data analysis used the Chi-square test and Spearman's correlation with p < 0.05.

Results

The average participants' serum PGE₂ levels were

SUBMITTER: Setiawan HW 

PROVIDER: S-EPMC8606836 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature