Transmission of cytomegalovirus via breast milk in low birth weight and premature infants: a systematic review and meta-analysis.

ABSTRACT:

Background

This study aimed to investigate the transmission of cytomegalovirus (CMV) via breast milk in low birth weight (LBW) and premature infants and its effects.

Methods

PubMed, Medline, Cochrane Library, and Embase were searched for studies (without language and time restriction) published before March 27, 2020, that examined the effect of CMV transmitted by breast milk on LBW and premature infants. The rates of breast milk-acquired CMV infection, CMV-related symptoms, and CMV-related sepsis-like syndrome (CMV-SLS) in LBW and premature infants were pooled from each study.

Results

Eighteen studies with 1920 LBW and premature infants were included. The pooled CMV infection rate from breast milk for infants fed untreated breast milk was significantly higher than tho

SUBMITTER: Hu X 

PROVIDER: S-EPMC8607598 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature