Early intervention of peri-implantitis and periodontitis using a mouse model.

ABSTRACT:

Background

Peri-implantitis is an inflammatory response to bacterial biofilm resulting in bone loss and can ultimately lead to implant failure. Because of the lack of predictable treatments available, a thorough understanding of peri-implantitis's pathogenesis is essential. The objective of this study is to evaluate and compare the response of acute induced peri-implantitis and periodontitis lesions after insult removal.

Methods

Implants were placed in one-month-old C57BL/6J male mice eight weeks post extraction of their left maxillary molars. Once osseointegrated, ligatures were placed around the implants and contralateral second molars of the experimental groups. Controls did not receive ligatures. After one week, half of the ligatures were removed, creating the ligature-r

SUBMITTER: Wong RL 

PROVIDER: S-EPMC8607848 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature