The cross-sectional association of cognition with diabetic peripheral and autonomic neuropathy-The GRADE study.

ABSTRACT:

Background

Studies examining whether measures of cognition are related to the presence of diabetic peripheral neuropathy (DPN) and/or cardiovascular autonomic neuropathy (CAN) are lacking, as are data regarding factors potentially explaining such associations.

Methods

Participants were from the Glycemia Reduction Approaches in Diabetes Study (GRADE) that examined 5047 middle-aged people with type 2 diabetes of <10 years of known duration. Verbal learning and immediate and delayed recall (memory) were assessed with the Spanish English Verbal Learning Test; frontal executive function and processing speed with the Digit Symbol Substitution Test; and ability to concentrate and organize data with word and animal fluency tests. DPN was assessed with the Michigan Neuropathy Screeni

SUBMITTER: Barzilay JI 

PROVIDER: S-EPMC8608739 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature