Characterisation and outcomes of patients referred to a regional cancer of unknown primary team: a 10-year analysis.

ABSTRACT:

Background

In the United Kingdom, national guidance published in 2010 recommended the establishment of specialist teams to improve clinical pathways for patients presenting with malignancies of undefined primary origin (MUO) and cancer of unknown primary (CUP). This study sought to define outcomes of patients referred to a regional MUO/CUP service.

Methods

Data were collected prospectively on all patients (n = 1225) referred to a regional CUP team over a 10-year period. Patient demographics, clinical, pathological and outcome data were recorded and analysed.

Results

Confirmed CUP (cCUP) was diagnosed in 25% of patients. A primary metastatic cancer was identified in 36%, 5% were diagnosed with provisional CUP (pCUP), 27% retained the diagnosis of MUO and in 8% a non-ca

SUBMITTER: Stares M 

PROVIDER: S-EPMC8608886 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature