Value of ¹⁸F-FDG PET/CT for predicting axillary pathologic complete response following neoadjuvant systemic therapy in breast cancer patients: emphasis on breast cancer subtype.

ABSTRACT:

Background

Neoadjuvant systemic therapy (NST) is a widely accepted initial treatment modality that can lead to pathologic downstaging of the axillary disease burden in breast cancer patients. Axillary response as well as baseline ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) uptake on positron emission tomography with computed tomography (PET/CT) differ between breast cancer subtypes. The value of baseline ¹⁸F-FDG PET/CT in predicting axillary response to NST is not yet established, possibly since breast cancer subtype was not taken into account. The purpose of this study was to investigate the value of baseline ¹⁸F-FDG PET/CT in predicting axillary response to NST with a specific emphasis on subtype.

Methods

PET-parameters derived from the pri

SUBMITTER: de Mooij CM 

PROVIDER: S-EPMC8609064 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature