Results availability and timeliness of registered COVID-19 clinical trials: interim cross-sectional results from the DIRECCT study.

ABSTRACT:

Objective

To examine how and when the results of COVID-19 clinical trials are disseminated.

Design

Cross-sectional study.

Setting

The COVID-19 clinical trial landscape.

Participants

285 registered interventional clinical trials for the treatment and prevention of COVID-19 completed by 30 June 2020.

Main outcome measures

Overall reporting and reporting by dissemination route (ie, by journal article, preprint or results on a registry); time to reporting by dissemination route.

Results

Following automated and manual searches of the COVID-19 literature, we located 41 trials (14%) with results spread across 47 individual results publications published by 15 August 2020. The most common dissemination route was preprints (n=25) followed by journal articl

SUBMITTER: Salholz-Hillel M 

PROVIDER: S-EPMC8609493 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature